What is IVF?

In-vitro fer­ti­liza­ti­on means that fer­ti­liza­ti­on takes place out­side the body “in a test tube.” Eggs and sperm meet in a petri dish so that the embryo can even­tual­ly be retur­ned to the ute­rus. World­wi­de, eight mil­li­on babies have seen the light of day thanks to this method.

  • Con­ven­tio­nal IVF

    A well-dosed hor­mo­n­al sti­mu­la­ti­on ensu­res the extra­c­tion of seve­ral oocytes and increa­ses the chan­ce of pregnan­cy.

    More about IVF
  • IVF Natu­rel­le / Mini-IVF

    Fewer hor­mo­nes are used here, making the tre­at­ment gent­ler on the pati­ent. The num­ber of oocytes is lower and the chan­ces of suc­cess per cycle are lower, but side effects and cos­ts are redu­ced.

    More about IVF Natu­rel­le
  • ICSI

    This method is pri­ma­ri­ly used when sperm qua­li­ty is sever­ely limi­t­ed. A sin­gle, careful­ly sel­ec­ted sperm is injec­ted direct­ly into the egg.

    More about ICSI

When IVF is recom­men­ded

  • If other tre­at­ment opti­ons (e.g. cycle moni­to­ring, hor­mo­n­al sti­mu­la­ti­on or inse­mi­na­ti­on) have been unsuc­cessful
  • In the case of limi­t­ed sperm qua­li­ty or low sperm counts
  • If the fallo­pian tubes are blo­cked or dama­ged
  • In the case of age-rela­ted limi­t­ed fer­ti­li­ty (e.g. from 40 years of age)

Who is IVF tre­at­ment sui­ta­ble for

Logo Ikon Cou­ples

IVF tre­at­ment can help cou­ples who­se desi­re to have child­ren has not been ful­fil­led despi­te other methods such as hor­mo­n­al sti­mu­la­ti­on or inse­mi­na­ti­on.

For cou­ples

Logo Ikon Les­bi­an cou­ples

Les­bi­an cou­ples can also ful­fill their desi­re to have child­ren with the help of IVF – for exam­p­le, with the help of donor sperm tre­at­ment.

For les­bi­an cou­ples

Logo Ikon Sin­gle women

For sin­gle women who want a child, IVF in com­bi­na­ti­on with donor sperm can be a sui­ta­ble opti­on.

For sin­gle women

Logo Ikon Women over 40

From around the age of 40, natu­ral fer­ti­li­ty decrea­ses signi­fi­cant­ly. IVF can impro­ve the chan­ces of pregnan­cy here, espe­ci­al­ly with good egg qua­li­ty.

For women over 40

Risks of IVF tre­at­ment

  • Hor­mo­n­al over­sti­mu­la­ti­on (OHSS) & mul­ti­ple pregnan­cy risk
  • Mini­mal risks of mal­for­ma­ti­ons
Schwangere Frau nach erfolgreicher PICSI Behandlung Frau macht sich Notizen zu Social Freezing Vorgang

Spe­cia­list assess­ment of IVF

Gold­stan­dard

IVF (in-vitro fer­ti­liza­ti­on) is one of the most estab­lished and suc­cessful methods in repro­duc­ti­ve medi­ci­ne world­wi­de. Our fer­ti­li­ty doc­tors con­sider IVF to be the gold stan­dard for many forms of infer­ti­li­ty – with high suc­cess rates and long-term pro­ven results.

Sup­ple­men­ta­ry tre­at­ments & addi­tio­nal opti­ons

Exten­ded sperm sel­ec­tion (PICSI)

In sel­ec­ted cases, we use modern methods for sperm sel­ec­tion – such as PICSI. The­se methods enable the sel­ec­tion of the most moti­le and gene­ti­cal­ly int­act sperm in order to impro­ve the fer­ti­liza­ti­on rate and embryo qua­li­ty.

Cryo­p­re­ser­va­ti­on (oocytes & embry­os)

Cryo­p­re­ser­va­ti­on enables the free­zing and long-term sto­rage of oocytes or embry­os – for exam­p­le, for fami­ly plan­ning or after IVF/ICSI tre­at­ment. Remai­ning fer­ti­li­zed oocytes can be fro­zen in the pro­nu­clear stage at ‑196 °C and later used for a new cycle wit­hout the need for ano­ther punc­tu­re. This shor­tens the tre­at­ment, pro­tects the body and pre­ser­ves fer­ti­li­ty in the long term.

Psy­cho­the­ra­peu­tic sup­port

During fer­ti­li­ty tre­at­ment, we offer psy­cho­the­ra­peu­tic sup­port on request. This sup­port can help to pro­cess emo­tio­nal stress and men­tal­ly streng­then the tre­at­ment pro­cess – for a holi­sti­cal­ly sup­port­i­ve envi­ron­ment.

Pro­ce­du­re of IVF tre­at­ment

At the pri­va­te cen­ter “Die Kin­der­wunsch­ärz­tin” in Munich, we accom­pa­ny you step by step through your IVF or ICSI tre­at­ment – indi­vi­du­al­ly, trans­par­ent­ly and with the grea­test care.

  1. Cycle start & first check-up

    Zu Beginn Ihres Zyklus erfol­gen Ultra­schall und Hor­mon­un­ter­su­chung (meist am 8.–11. Zyklus­tag), um den opti­ma­len Start­zeit­punkt zu bestim­men.

    We wait for the start of the cycle first. Depen­ding on your cycle length, the first ultra­sound and hor­mo­ne exami­na­ti­on takes place bet­ween the 8th and 11th day of the cycle. This exami­na­ti­on ser­ves to assess the hor­mo­ne sta­tus and the deve­lo­p­ment of the fol­lic­les in order to be able to plan fur­ther tre­at­ment indi­vi­du­al­ly.

    Make an appoint­ment
  2. Sti­mu­la­ti­on & moni­to­ring (8–12 days)

    Die Eier­stö­cke wer­den hor­mo­nell sti­mu­liert, damit meh­re­re Eibläs­chen gleich­zei­tig her­an­rei­fen.

    Growth is che­cked regu­lar­ly with ultra­sound and blood tests. During the sti­mu­la­ti­on pha­se, which lasts about 8 to 12 days, the fol­lic­les matu­re through an indi­vi­du­al­ly tail­o­red hor­mo­n­al sti­mu­la­ti­on of the ova­ries. The admi­nis­tra­ti­on of a so-cal­led GnRH ago­nist or ant­ago­nist pre­vents pre­ma­tu­re ovu­la­ti­on. Regu­lar ultra­sound and blood tests help to moni­tor the growth of the fol­lic­les and deter­mi­ne the opti­mal time for egg retrie­val.

  3. Egg retrie­val (punc­tu­re)

    Kurz vor dem Eisprung wer­den die Eizel­len in einem kur­zen Ein­griff ent­nom­men – meist in leich­ter Nar­ko­se.

    When the fol­lic­les are lar­ge enough, the egg retrie­val is sche­du­led. A spe­cial hor­mo­ne injec­tion trig­gers the final matu­ra­ti­on of the oocytes. Appro­xi­m­ate­ly 36 hours later, the oocytes are extra­c­ted from the fol­lic­les in a small sur­gi­cal pro­ce­du­re under ultra­sound gui­dance. The pro­ce­du­re only takes a few minu­tes and is usual­ly per­for­med under short anes­the­sia. If the­re are few fol­lic­les, the punc­tu­re can also be per­for­med wit­hout anes­the­sia.

  4. Fer­ti­liza­ti­on in the labo­ra­to­ry (IVF/ICSI)

    Die gewon­ne­nen Eizel­len wer­den im Labor mit den Sper­mi­en zusam­men­ge­bracht – oder bei der ICSI wird ein ein­zel­nes Sper­mi­um direkt in die Eizel­le inji­ziert.

    On the day of egg retrie­val, the part­ner sub­mits his sperm sam­ple. In the embryo­lo­gi­cal labo­ra­to­ry, oocytes and sperm are brought tog­e­ther (IVF) or, in the case of ICSI, a sin­gle sperm is injec­ted direct­ly into the oocy­te. The next day, it is che­cked how many oocytes have been suc­cessful­ly fer­ti­li­zed and are deve­lo­ping into embry­os.

  5. Embryo trans­fer (day 3 or 5)

    Nach 3 bis 5 Tagen wird der Embryo in die Gebär­mut­ter ein­ge­setzt – ein kur­zer, schmerz­frei­er Ein­griff.

    Depen­ding on the deve­lo­p­ment of the embry­os, the trans­fer takes place on the third or fifth day after fer­ti­liza­ti­on. The embryo is inser­ted into the ute­rus with a fine cathe­ter. The pro­ce­du­re is pain­less and only takes a few minu­tes

  6. Pregnan­cy test (~14 days later)

    Etwa zwei Wochen nach dem Embryo­trans­fer erfolgt der Schwan­ger­schafts­test.

    Tog­e­ther we will dis­cuss the result and the next steps. The pregnan­cy test can be car­ri­ed out after about 14 days. We will dis­cuss the result with you and cla­ri­fy the next steps. If the test is nega­ti­ve, we will ana­ly­ze the cau­ses and advi­se you indi­vi­du­al­ly on fur­ther opti­ons.

  1. Ano­ther title

    Text for tre­at­ment 2’s first item.

    Make an appoint­ment
  2. Fer­ti­liza­ti­on (IVF/ICSI)

    Lab step; We update you.

  3. Egg retrie­val (short out­pa­ti­ent)

    You rest; We coll­ect oocytes.

  4. Sti­mu­la­ti­on & moni­to­ring (10–12 days)

    We tail­or meds; You attend scans.

Schwangere Frau nach PRP Behandlung an den Eierstöcken

Why IVF/ICSI with us in Munich?

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  • Per­so­nal and con­ti­nuous sup­port

    With us, you will be accom­pa­nied by the same doc­tor from the initi­al con­sul­ta­ti­on and dia­gno­stics to the embryo trans­fer.

  • Indi­vi­du­al­ly tail­o­red tre­at­ment

    We offer all com­mon IVF and ICSI pro­ce­du­res – from clas­sic IVF to mini-IVF and IVF Natu­rel­le.

  • Own labo­ra­to­ry

    Fast results and full trans­pa­ren­cy: Our in-house hor­mo­ne labo­ra­to­ry enables fast eva­lua­tions and clear com­mu­ni­ca­ti­on.

  •  Cen­tral loca­ti­on & fle­xi­ble con­sul­ta­ti­on hours

    Our fer­ti­li­ty cen­ter is cen­tral­ly loca­ted in Munich – with appoint­ments ear­ly in the mor­ning or in the evening to reli­e­ve your ever­y­day life

IVF suc­cess rates: Your chan­ces of get­ting pregnant

Accor­ding to the cur­rent IVF regis­ter, the avera­ge pregnan­cy rate after one tre­at­ment is 31.4%, and the birth rate is 22.5%. After four tre­at­ment cycles, the avera­ge pregnan­cy rate increa­ses to appro­xi­m­ate­ly 66%.

The suc­cess rates are high­ly depen­dent on age: the pregnan­cy rates for women up to 34 years of age are on avera­ge 41%, from 35 – 39 years of age appro­xi­m­ate­ly 35% and for 40 – 42 year olds appro­xi­m­ate­ly 20%.

We would be hap­py to inform you indi­vi­du­al­ly about your chan­ces in our fer­ti­li­ty cen­ter.

Make an appoint­ment
Logo Ikon

Chan­ces of a natu­ral pregnan­cy & with IVF

During your con­sul­ta­ti­on, we will explain your per­so­nal chan­ces of suc­cess in detail.

Diagramm - Fehlgeburtenrisiko

Cal­cu­la­te your esti­ma­ti­on

Results based on your age

After 1 IVF/ICSI cycle
0% Pregnan­cy rate
0% Birth rate
After 4 IVF/ICSI cycles
0% Pregnan­cy rate
0% Birth rate

Source: Ger­man IVF Regis­ter

Read our pati­ent tes­ti­mo­ni­als

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Cos­ts: ICSI signi­fi­cant­ly more expen­si­ve than IVF

IVF tre­at­ment is tech­ni­cal­ly much simp­ler and also che­a­per. The cos­ts of an ICSI cycle are around €6,500*, an IVF cycle cos­ts around €3,300 (plus addi­tio­nal cos­ts such as anes­the­sia and medi­ca­ti­on)* – a big dif­fe­rence. Depen­ding on the tariff, pri­va­te health insu­rance com­pa­nies some­ti­mes cover the com­ple­te cos­ts. More infor­ma­ti­on can be found in our cost over­view.

To the cost over­view
IVF cos­ts from €3,300

In-vitro fer­ti­liza­ti­on (IVF) includes sti­mu­la­ti­on of the ova­ries, egg retrie­val, fer­ti­liza­ti­on in the labo­ra­to­ry and embryo trans­fer into the ute­rus. The basic cos­ts include medi­cal ser­vices and labo­ra­to­ry work.

IVF cycle (basic)

~€3,300

Cos­ts for medi­ca­ti­on and anes­the­sia (depen­ding on indi­vi­du­al needs)

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ICSI cos­tsfrom €6,300

Intra­cy­to­plas­mic sperm injec­tion (ICSI) is a fur­ther deve­lo­p­ment of IVF. A sin­gle sperm is injec­ted direct­ly into the oocy­te under the micro­scope – espe­ci­al­ly in the case of limi­t­ed sperm qua­li­ty or unsuc­cessful IVF.

Cos­ts for medi­ca­ti­on and anes­the­sia (depen­ding on indi­vi­du­al needs)

Make an appoint­ment
Addi­tio­nal cos­ts — medi­ca­ti­on, anes­the­sia, cryo­p­re­ser­va­ti­on

In addi­ti­on to the tre­at­ment cos­ts, fur­ther expen­ses may ari­se – depen­ding on the the­ra­py and your indi­vi­du­al needs. The­se include:

  • Medi­ca­ti­on for hor­mo­n­al sti­mu­la­ti­on (approx. €400 – €1,500)
  • Anes­the­sia during egg retrie­val
  • Cryo­p­re­ser­va­ti­on (free­zing) of oocytes or embry­os, e.g. for social free­zing (sto­rage approx. €380 / year)
Insu­rance cover — what is typi­cal­ly cover­ed

The covera­ge depends hea­vi­ly on your insu­rance.

Pri­va­te health insu­rance (PKV):Depen­ding on the tariff, many or even all tre­at­ment cos­ts are cover­ed if the­re is a medi­cal indi­ca­ti­on (e.g. orga­nic cau­se of infer­ti­li­ty). The­re are usual­ly no age limits or limi­ta­ti­ons on the num­ber of tre­at­ment cycles.

Sta­tu­to­ry health insu­rance (GKV):Sin­ce our cen­ter is a pri­va­te cen­ter, the cos­ts are gene­ral­ly not reim­bur­sed by the GKV. Howe­ver, tho­se with sta­tu­to­ry insu­rance can be trea­ted as self-pay­ers.

Plea­se inqui­re in advan­ce with your insu­rance com­pa­ny about pos­si­ble reim­bur­se­ments – we will be hap­py to sup­port you with the appli­ca­ti­on.

Single Mom mit Baby auf dem Arm nach künstlicher Befruchtung beim Kinderwunschzentrum in München

Fre­quent­ly asked ques­ti­ons about IVF / ICSI

All rele­vant ques­ti­ons about arti­fi­ci­al inse­mi­na­ti­on, pro­ce­du­re, chan­ces of suc­cess and next steps.

What is the dif­fe­rence bet­ween IVF and ICSI?

Both pro­ce­du­res belong to arti­fi­ci­al inse­mi­na­ti­on. In IVF (in-vitro fer­ti­liza­ti­on), oocytes and sperm meet in the labo­ra­to­ry to fer­ti­li­ze natu­ral­ly. In ICSI (intra­cy­to­plas­mic sperm injec­tion), on the other hand, a sin­gle sperm is injec­ted direct­ly into the oocy­te – useful in the case of limi­t­ed sperm qua­li­ty or if a pre­vious IVF was unsuc­cessful.

What is bet­ter – IVF or ICSI?

ICSI can impro­ve the chan­ces of fer­ti­liza­ti­on for cer­tain cau­ses of infer­ti­li­ty, but is not fun­da­men­tal­ly more suc­cessful than IVF. Cur­rent stu­dies (e.g. Dang et al., Lan­cet 2021, Bou­let et al. JAMA 2015) show that the suc­cess rates are com­pa­ra­ble with nor­mal male fer­ti­li­ty. Howe­ver, ICSI is more expen­si­ve and should only be used if the­re is a medi­cal indi­ca­ti­on.

Do women over 40 have bet­ter chan­ces of suc­cess with ICSI?

Not neces­s­a­ri­ly. Stu­dies show that in women over 40 years of age and nor­mal sperm qua­li­ty, the­re is no advan­ta­ge of ICSI over IVF (Tan­nus et al., Hum Reprod 2017). The age of the woman, the oocy­te reser­ve and the qua­li­ty of the oocytes obtai­ned play a much grea­ter role in the suc­cess than the choice bet­ween IVF or ICSI. The­r­e­fo­re, we recom­mend plan­ning the tre­at­ment indi­vi­du­al­ly and holi­sti­cal­ly.

Is the­re a natu­ral method for IVF?

Yes, the so-cal­led natu­ral or mild IVF (natu­ral cycle IVF) is a gent­ler vari­ant of arti­fi­ci­al inse­mi­na­ti­on. The cycle is lar­ge­ly car­ri­ed out wit­hout hor­mo­n­al sti­mu­la­ti­on. The method is par­ti­cu­lar­ly sui­ta­ble for women with a regu­lar cycle, low oocy­te reser­ve or into­le­rance to hor­mo­nes. Sin­ce usual­ly only one oocy­te matures per cycle, the chan­ces of suc­cess are some­what lower than with con­ven­tio­nal IVF. In return, the tre­at­ment is much bet­ter tole­ra­ted phy­si­cal­ly, the risk of an over­sti­mu­la­ti­on syn­dro­me is eli­mi­na­ted, and the egg retrie­val can often be car­ri­ed out wit­hout anes­the­sia. For many pati­ents, natu­ral IVF is a gent­le and safe alter­na­ti­ve that enables seve­ral tre­at­ment cycles in a row.

What hap­pens to fer­ti­li­zed oocytes that are not used?

Not all fer­ti­li­zed oocytes are trans­fer­red imme­dia­te­ly. Excess oocytes can be fro­zen in the so-cal­led pro­nu­clear stage and used for later trans­fers. This pro­ce­du­re is cal­led cryo­p­re­ser­va­ti­on and saves ano­ther egg retrie­val.

How long does an IVF or ICSI tre­at­ment take in total?

The dura­ti­on depends hea­vi­ly on the indi­vi­du­al requi­re­ments. From the first dia­gno­sis to the pos­si­ble pregnan­cy, the tre­at­ment can take seve­ral weeks to seve­ral months. The actu­al hor­mo­ne sti­mu­la­ti­on usual­ly com­pri­ses 8 to 12 days, during which the oocy­te matu­ra­ti­on is regu­lar­ly che­cked by ultra­sound. After the punc­tu­re and fer­ti­liza­ti­on, it takes a few days to the embryo trans­fer – then fol­lows the implan­ta­ti­on pha­se.

Does the health insu­rance com­pa­ny cover the cos­ts of IVF or ICSI tre­at­ment?

The covera­ge depends on the respec­ti­ve insu­rance com­pa­ny. Pri­va­te health insu­rance com­pa­nies often cover the tre­at­ment com­ple­te­ly if the­re is an orga­nic cau­se of infer­ti­li­ty – even for unmar­ried cou­ples. With most pri­va­te tariffs, the num­ber of attempts is not limi­t­ed, pro­vi­ded that the expec­ted pro­ba­bi­li­ty of suc­cess is over 15%. Sta­tu­to­ry health insu­rance com­pa­nies only cover the cos­ts par­ti­al­ly and under cer­tain con­di­ti­ons. We will be hap­py to sup­port you in cla­ri­fy­ing the reim­bur­se­ment of cos­ts with your insu­rance com­pa­ny.

What are the risks of IVF?

Pos­si­ble IVF risks include hor­mo­n­al over­sti­mu­la­ti­on (OHSS), which depends on age, oocy­te reser­ve and hor­mo­ne dose and occurs in appro­xi­m­ate­ly 1–10% of women; seve­re forms are very rare at appro­xi­m­ate­ly 0.2%. The risk of mul­ti­ple pregnan­ci­es depends on the num­ber of embry­os trans­fer­red and can be redu­ced to appro­xi­m­ate­ly 1% by trans­fer­ring a sin­gle embryo (sin­gle embryo trans­fer). Accor­ding to cur­rent sci­en­ti­fic know­ledge, the risk of breast can­cer is not increased after IVF. The risk of mal­for­ma­ti­ons is appro­xi­m­ate­ly 2–3% for all child­ren and appro­xi­m­ate­ly 4–6% for IVF/ICSI child­ren, depen­ding on the stu­dy; this small plus seems to be more rela­ted to the cou­ple’s infer­ti­li­ty than to the tre­at­ment its­elf.

We would be hap­py to advi­se you indi­vi­du­al­ly on your per­so­nal risks and addi­tio­nal sup­port ser­vices such as TCM, nut­ri­tio­nal advice or psy­cho­lo­gi­cal sup­port in our fer­ti­li­ty cen­ter.

How can I sup­port the suc­cess of fer­ti­li­ty tre­at­ment?

A healt­hy life­style can addi­tio­nal­ly impro­ve the chan­ces of suc­cess. A balan­ced diet, taking folic acid, suf­fi­ci­ent exer­cise and abs­tai­ning from nico­ti­ne and alco­hol are important. Psy­cho­lo­gi­cal sta­bi­li­ty and suf­fi­ci­ent sleep also have a posi­ti­ve effect on the hor­mo­ne balan­ce and implan­ta­ti­on. We would be hap­py to advi­se you indi­vi­du­al­ly on sup­port­i­ve mea­su­res in our fer­ti­li­ty cen­ter.